There is a direct correlation between being overweight and iron deficiency. Physiological changes occur in obese adipose cells that contribute to the development of iron deficiency (ID) and iron deficiency anemia (IDA). These changes disrupt the normal iron metabolic checks and balances. Furthermore, bariatric surgery can lead to long-term ID and IDA. Oral iron supplementation may not be effective for many of these patients. Intravenous iron infusions can significantly increase the quality of life for individuals experiencing this condition but are also associated with potentially serious complications. Adequate knowledge about intravenous (IV) iron administration can greatly increase the safety of this beneficial therapy. This review article explains the relationship between obesity, ID/IDA, bariatric surgery and the safe administration of IV iron.
Keyphrases
- iron deficiency
- weight loss
- bariatric surgery
- metabolic syndrome
- insulin resistance
- obese patients
- type diabetes
- weight gain
- end stage renal disease
- adipose tissue
- high dose
- chronic kidney disease
- newly diagnosed
- induced apoptosis
- stem cells
- risk factors
- low dose
- skeletal muscle
- oxidative stress
- bone marrow
- mesenchymal stem cells
- patient reported
- patient reported outcomes
- cell death