Kidney oxygenation, perfusion and blood flow in people with and without type 1 diabetes.
Jens Christian LaursenNiels Søndergaard HeinrichBryan HaddockIda Kirstine Bull RasmussenChristian Stevns HansenHenrik Bo Wiberg LarssonPer-Henrik GroopPetter BjornstadMarie Frimodt-MøllerUlrik Bjørn AndersenEllen BurgessPublished in: Clinical kidney journal (2022)
Participants with T1D and albuminuria exhibited higher medullary oxygenation than CONs, despite lower cortical perfusion and renal artery blood flow. This might reflect perturbed kidney energetics leading to a higher setpoint of medullary oxygenation in T1D. Lower cortical oxygenation and renal artery blood flow were associated with higher UACR and lower eGFR in T1D.