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Alterations of local functional connectivity in lifespan: A resting-state fMRI study.

Xin WenHui HeLi DongJunjie ChenJie YangHao GuoCheng LuoDezhong Yao
Published in: Brain and behavior (2020)
These results might suggest that the decline of executive control and intrinsic cognitive ability in the aging population was related to the decline of functional connectivity in VN, SMN, and DMN. Meanwhile, BGN might play a regulatory role in the aging process to compensate for the dysfunction of other functional systems. Our findings may provide important neuroimaging evidence for exploring the brain functional mechanism in lifespan.
Keyphrases
  • resting state
  • functional connectivity
  • oxidative stress
  • transcription factor
  • drug induced