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Acute antiepileptic drug use in intensive care units.

Bernd J VorderwülbeckeGregor LichtnerFalk von DincklageMartin Holtkamp
Published in: Journal of neurology (2018)
One out of eleven ICU patients receives acute AEDs, in almost half of cases for non-seizure indications. Acute AED use is a marker for intracranial ICU indications and prolonged ICU treatments. Usually, newer-generation AEDs are employed with favourable pharmacokinetic and safety profiles. However, whenever possible, acutely started AED should be discontinued before discharge from ICU.
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