A multi-center prospective study of re-irradiation with bevacizumab and temozolomide in patients with bevacizumab refractory recurrent high-grade gliomas.

Karan S DixitSean SachdevChristina AmideiPriya KumthekarTim J KruserVinai GondiSean GrimmRimas V LukasMartin Kelly NicholasSteven J ChmuraAngela J FoughtMinesh MehtaJeffrey J Raizer

Published in: Journal of neuro-oncology (2021)

Re-irradiation with bevacizumab and temozolomide is a safe and feasible salvage treatment for patients with large volume bevacizumab-refractory high-grade glioma. Patients further from their initial radiotherapy may derive greater benefit with this regimen.

Keyphrases

high grade
metastatic colorectal cancer
newly diagnosed
low grade
end stage renal disease
ejection fraction
chronic kidney disease
radiation induced
early stage
radiation therapy
prognostic factors
peritoneal dialysis
squamous cell carcinoma
locally advanced