Magnetic Resonance Imaging of Mouse Cerebral Cavernomas Reveal Differential Lesion Progression and Variable Permeability to Gadolinium.
Delaney G FisherKhadijeh A SharifiE Zeynep UlutasJeyan S KumarM Yashar S KalaniG Wilson MillerRichard J PricePetr TvrdikPublished in: Arteriosclerosis, thrombosis, and vascular biology (2023)
Our results lay a foundation for better understanding individual lesion properties and provide a comprehensive preclinical platform for testing new drug and gene therapies for controlling cerebral cavernous malformations.
Keyphrases
- magnetic resonance imaging
- subarachnoid hemorrhage
- genome wide
- contrast enhanced
- cerebral ischemia
- copy number
- high throughput
- brain injury
- computed tomography
- endothelial cells
- cerebral blood flow
- single cell
- dna methylation
- emergency department
- stem cells
- cell therapy
- gene expression
- magnetic resonance
- adverse drug
- drug induced