Establishment of transfusion-relevant bacteria reference strains for red blood cells.
Marcel PraxEva Spindler-RaffelCarl Peter McDonaldJennifer BearneMasahiro SatakeMoe KozakaiJulieta RojoKay-Martin O HanschmannBernd LambrechtUdo GrundmannNiamh O'FlahertyAgata KlimekIsabelle Bekeredjian-DingBirgit S GathofMelanie StörmerSusanne SüßnerClaudia RenkeCheuk Kwong LeeCornelius KnabbeTanja VollmerShawn D KeilMarley E ShippsStephen J WagnerUte JentschXoliswa MpumlwanaMarc CloutierPeter BringmannThea LuSandra Ramirez-ArcosYuntong KouOleg Krutnull nullPublished in: Vox sanguinis (2020)
The results illustrate the importance of conducting comprehensive studies to establish well-characterized reference strains, which can be a tool to assess strategies and methods used to ameliorate blood safety. The WHO Expert Committee on Biological Standardization adopted the five successful strains as official RBCC reference strains. Our study also highlights the relevance of visual inspection to interdict contaminated RBC units.