Optimization to detect TP53 mutations in circulating cell-free tumor DNA from patients with serous epithelial ovarian cancer.
Yu Ran ParkYong-Man KimShin Wha LeeHa Young LeeGun Eui LeeJong-Eun LeeYoung-Tak KimPublished in: Obstetrics & gynecology science (2018)
This study developed detection methods for TP53 mutations in cfDNA in ovarian cancer patients using dPCR. The results demonstrated that there are the same TP53 mutations in both ovarian cancer tissue and cfDNA.