Login / Signup

Hepatic interleukin 32 attenuates liver injury through repression of necroptosis in cholestasis.

Xiuru MaoXiaoxun ZhangZiqian XuNan ZhaoLei FuShifang PengJin Chai
Published in: Journal of digestive diseases (2023)
In conclusion, IL32 is negatively correlated with necroptosis in cholestatic patients. What's more, IL32 is induced by p-Akt and effectively attenuates necroptosis in the mouse models of ANIT/1%LCA-induced cholestasis.
Keyphrases
  • patient reported outcomes
  • liver injury
  • drug induced
  • mouse model
  • ejection fraction
  • end stage renal disease
  • endothelial cells
  • newly diagnosed
  • high glucose
  • chronic kidney disease
  • peritoneal dialysis
  • liver fibrosis