Hepatic interleukin 32 attenuates liver injury through repression of necroptosis in cholestasis.
Xiuru MaoXiaoxun ZhangZiqian XuNan ZhaoLei FuShifang PengJin ChaiPublished in: Journal of digestive diseases (2023)
In conclusion, IL32 is negatively correlated with necroptosis in cholestatic patients. What's more, IL32 is induced by p-Akt and effectively attenuates necroptosis in the mouse models of ANIT/1%LCA-induced cholestasis.