Orthostatic heart rate changes in patients with autonomic failure caused by neurodegenerative synucleinopathies.
Lucy Norcliffe-KaufmannHoracio KaufmannJose Alberto PalmaCyndya A ShibaoItalo BiaggioniAmanda C PeltierWolfgang SingerPhillip A LowDavid S GoldsteinChristopher H GibbonsRoy FreemanDavid Robertsonnull nullPublished in: Annals of neurology (2018)
A blunted HR increase during hypotension suggests a neurogenic cause. A ΔHR/ΔSBP ratio < 0.5 bpm/mmHg is diagnostic of neurogenic OH. Ann Neurol 2018;83:522-531.