Stromal protein βig-h3 reprogrammes tumour microenvironment in pancreatic cancer.

Delphine GoehrigJérémy NigriRémi SamainZhichong WuPaola CappelloGaëlle GabianeXinyi ZhangYajie ZhaoIn-San KimMarie ChanalRoberta CurtoValerie HervieuChristelle de La FouchardièreFrancesco NovelliPascale MilaniRichard TomasiniCorinne BousquetPhilippe BertolinoAna Hennino

Published in: Gut (2018)

Our data indicate that targeting stromal extracellular matrix protein βig-h3 improves the antitumoural response and consequently reduces tumour weight. Our findings present βig-h3 as a novel immunological target in pancreatic cancer.

Keyphrases

extracellular matrix
bone marrow
protein protein
stem cells
amino acid
physical activity
electronic health record
weight loss
cancer therapy
drug delivery
data analysis
body weight
deep learning
artificial intelligence