Disparities in ABO blood type determination across diverse ancestries: a systematic review and validation in the All of Us Research Program.
Kiana L MartinezAndrew KleinJennifer R MartinChinwuwanuju U SampsonJason B GilesMadison L BeckKrupa BhaktaGino QuatraroJuvie FarolJason H KarnesPublished in: Journal of the American Medical Informatics Association : JAMIA (2024)
Our results highlight the lack of transferability of tSNPs across ancestries and potential exacerbation of disparities in genomic research for underrepresented populations. This is especially relevant as more diverse cohorts are made publicly available.
Keyphrases
- chronic obstructive pulmonary disease
- affordable care act
- quality improvement
- solid phase extraction
- copy number
- healthcare
- gene expression
- risk assessment
- dna methylation
- genetic diversity
- high resolution
- extracorporeal membrane oxygenation
- respiratory failure
- acute respiratory distress syndrome
- mechanical ventilation