Immediate effect of anti-VEGF injections on optic nerve head: Correlation between intraocular pressure and anatomical peripapillary changes.
Pasquale ViggianoRosa BuonamassaMaria Oliva GrassiGiacomo BosciaEnrico BorrelliLuca LandiniFederica EvangelistaMaria Giovanna MalerbaGiovanni AlessioFrancesco BosciaPublished in: European journal of ophthalmology (2023)
We reported acute IOP changes that are associated with reduced RNFL thickness in a group of patients undergoing intravitreal injections of anti-VEGF drugs for neovascular age-related macular degeneration. Moreover, topographical sub-analysis revealed that the nasal RNFL region is most prone to IOP fluctuations. This finding may explain the sudden visual acuity change in patients immediately after injection and may sustain injuries to optic nerve head structures producing glaucomatous damage.
Keyphrases
- optic nerve
- age related macular degeneration
- optical coherence tomography
- vascular endothelial growth factor
- patients undergoing
- end stage renal disease
- ultrasound guided
- endothelial cells
- diabetic retinopathy
- newly diagnosed
- ejection fraction
- chronic kidney disease
- oxidative stress
- liver failure
- platelet rich plasma
- high resolution
- extracorporeal membrane oxygenation
- patient reported
- mass spectrometry