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Antitumor Activity of Simvastatin in Preclinical Models of Mantle Cell Lymphoma.

Juliana Carvalho SantosNúria Profitós-PelejàMarcelo Lima RibeiroGael Roué
Published in: Cancers (2022)
Altogether, these data provide the first preclinical insight into the effect of simvastatin against MCL cells, suggesting that this agent might be considered for repurpose as a precise MCL therapy.
Keyphrases
  • induced apoptosis
  • cell therapy
  • cell cycle arrest
  • big data
  • endoplasmic reticulum stress
  • oxidative stress
  • stem cells
  • signaling pathway
  • mesenchymal stem cells
  • machine learning
  • deep learning
  • replacement therapy