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lncRNA MALAT1 Promotes Diabetic Nephropathy Progression via miR-15b-5p/TLR4 Signaling Axis.

Zijun YangDongxu SongYulin WangLin Tang
Published in: Journal of immunology research (2022)
These results indicate that reduced MALAT1 ameliorates HG-stimulated HK-2 cell damage through an inhibition of the miR-15b-5p/TLR4 axis. MALAT1 may serve as a biomarker and potential therapeutic target for DN.
Keyphrases
  • diabetic nephropathy
  • toll like receptor
  • inflammatory response
  • immune response
  • single cell
  • cell therapy
  • nuclear factor
  • long non coding rna
  • mouse model
  • stem cells
  • fluorescent probe
  • bone marrow
  • living cells