People With Parkinson's Disease Exhibit Reduced Cognitive and Motor Cortical Activity When Undertaking Complex Stepping Tasks Requiring Inhibitory Control.
Paulo H S PelicioniStephen R LordYoshiro OkuboDaina L SturnieksJasmine Charlotte Christiane MenantPublished in: Neurorehabilitation and neural repair (2020)
In contrast to the HOA, the PD group demonstrated reduced cortical activity in the DLPFC, SMA, and PMC during the more complex stepping tasks requiring inhibitory control. This may reflect subcortical and/or multiple pathway damage with subsequent deficient use of cognitive and motor resources.