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[General mechanisms of the pathogenesis of neurodenerative and cerebrovascular diseases and the possibilities of their correction].

O S LevinA N BogolepovaV Yu Lobzin
Published in: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (2022)
The recent research has revealed several common pathogenetic mechanisms underlying both vascular and neurodegenerative processes. This refers to chronic cerebral hypoperfusion, pathology of neurovascular units and the blood-brain barrier. The process of brain recovery in various lesions is realized due to the mechanisms of neuroplasticity. Using the example of Cerebrolysin, which has a multimodal effect, which includes an effect on the blood-brain barrier, a neurotrophic effect, an improvement in the drainage function of the brain, an anti-inflammatory effect, a direct effect on neurovascular units, the advantage of simultaneous action on various links of pathogenesis can be shown.
Keyphrases
  • anti inflammatory
  • white matter
  • pain management
  • cerebral ischemia
  • chronic pain
  • cognitive impairment
  • blood brain barrier
  • functional connectivity