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Extensive acute and sustained changes to neutrophil proteomes post-SARS-CoV-2 infection.

Merete B LongAndrew J M HowdenHolly R KeirChristina M RollingsYan Hui GiamThomas PembridgeLilia DelgadoHani Abo-LeyahAmy F LloydGabriel SollbergerRebecca HullAmy GilmourChloe HughesBenjamin J M NewDiane CassidyAmelia ShoemarkHollian RichardsonAngus I LamondDoreen A CantrellJames D ChalmersAlejandro J Brenes
Published in: The European respiratory journal (2024)
SARS-CoV-2 infection results in the sustained presence of circulating neutrophils with distinct proteomes suggesting altered metabolic and immunosuppressive profiles and altered capacities to respond to migratory signals and cues from other immune cells, pathogens or cytokines.
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