Injectable long-acting formulations (ILAFs) and manufacturing techniques.
Kosheli Thapa MagarHamza BoucettaZongmin ZhaoYing XuZhengxia LiuWei HePublished in: Expert opinion on drug delivery (2024)
ILAFs are sustained-release formulations with extended activity, which can improve patient compliance. ILAFs are designed to deliver APIs like proteins and peptides and extend their half-life over days to months. The specific properties of each ILAF preparation, such as extended-release and improved drug targeting capabilities, make them an effective approach for precise and focused therapy. Furthermore, this is especially helpful for biopharmaceuticals with short biological half-lives and low stability since most environmental conditions can protect them from sustained-release delivery methods.