Response to PD1 inhibition in conventional chondrosarcoma.
Michael J WagnerRobert W RicciottiJose MantillaElizabeth T LoggersSeth M PollackLee D CranmerPublished in: Journal for immunotherapy of cancer (2018)
Conventional chondrosarcoma may be sensitive to checkpoint inhibitors. Further, this case demonstrates clearly the phenomenon of pseudo-progression in this disease, a factor that must be considered in the design of clinical trials and clinical care. This case supports additional study of immunomodulatory agents in this deadly disease.