The effectiveness of phototherapy for surface decontamination against SARS-Cov-2. A systematic review.
Susyane Vieira de OliveiraFilipe Danilo das NevesDaniela Carvalho Dos SantosMariana Bernardes Batista MonteiroMaristela S SpangheroBeatriz Nascimento MottaIgor Pereira de OliveiraMaria Fernanda Setúbal Destro RodriguesAdriana Lino Dos Santos FrancoRebeca Boltes CecattoPublished in: Journal of biophotonics (2022)
COVID-19 appeared in December 2019, needing efforts of science. Besides, a range of light therapies (photodynamic therapy, ultraviolet [UV], laser) has shown scientific alternatives to conventional decontamination therapies. Investigating the efficacy of light-based therapies for environment decontamination against SARS-CoV2, a PRISMA systematic review of Phototherapies against SARS-CoV or MERS-CoV species discussing changes in viral RT-PCR was done. After searching MEDLINE/PubMed, EMBASE, and Literatura Latino-Americana e do Caribe em Ciências da Saúde we have found studies about cell cultures irradiation (18), blood components irradiation (10), N95 masks decontamination (03), inanimate surface decontamination (03), aerosols decontamination (03), hospital rooms irradiation (01) with PDT, LED, and UV therapy. The best quality results showed an effective low time and dose UV irradiation for environments and inanimate surfaces without human persons as long as the devices have safety elements dependent on the surfaces, viral charge, humidity, radiant exposure. To interpersonal contamination in humans, PDT or LED therapy seems very promising and are encouraged.
Keyphrases
- sars cov
- photodynamic therapy
- respiratory syndrome coronavirus
- systematic review
- endothelial cells
- healthcare
- radiation induced
- meta analyses
- public health
- risk assessment
- cell therapy
- fluorescence imaging
- drinking water
- biofilm formation
- stem cells
- radiation therapy
- cystic fibrosis
- mesenchymal stem cells
- heavy metals
- health risk
- drug induced
- candida albicans
- induced pluripotent stem cells
- water soluble