Genomic Landscape of Advanced Solid Tumors in Circulating Tumor DNA and Correlation With Tissue Sequencing: A Single Institution's Experience.

Lorenzo GerratanaMichael MovarekFiras H WehbeNeelima KatamDevalingam Mahalingam Jeannine DonahueAmi ShahYoung Kwang Chae Mary F MulcahyDean TsarwhasVictoria VillaflorAparna KalyanMaha H A Hussain Jyoti D PatelSunandana ChandraLeonidas C PlataniasWilliam J Gradishar Massimo CristofanilliAmir Behdad

Published in: JCO precision oncology (2022)

The study provided new insights into the ctDNA mutational landscape across solid tumors, suggesting new hypotheses-generating data and caveats for future histotype-agnostic workflows integrated with tissue-based biomarkers such as TMB.

Keyphrases

circulating tumor
cell free
circulating tumor cells
single cell
electronic health record
gene expression
current status
single molecule
artificial intelligence
data analysis
deep learning