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Unraveling multi-scale neuroimaging biomarkers and molecular foundations for schizophrenia: A combined multivariate pattern analysis and transcriptome-neuroimaging association study.

Yanmin PengChao ChaiKaizhong XueJie TangSijia WangQian SuChongjian LiaoGuoshu ZhaoShaoying WangNannan ZhangZhihui ZhangMinghuan LeiFeng LiuMeng Liang
Published in: CNS neuroscience & therapeutics (2024)
This study highlights the potential of multi-scale ReHo as a valuable neuroimaging biomarker in the diagnosis of schizophrenia. By elucidating the complex molecular basis underlying the ReHo alterations of this disorder, this study not only enhances our understanding of its pathophysiology, but also pave the way for future advancements in genetic diagnosis and treatment of schizophrenia.
Keyphrases
  • bipolar disorder
  • gene expression
  • dna methylation
  • genome wide
  • rna seq