Secondary Cytoreduction and Carboplatin Hyperthermic Intraperitoneal Chemotherapy for Platinum-Sensitive Recurrent Ovarian Cancer: An MSK Team Ovary Phase II Study.

Oliver ZivanovicDennis S ChiQin ZhouAlexia E Iasonos Jason A Konner Vicky MakkerRachel N GrishamAmy K BrownStacy NerenstoneJohn P DiazEric D SchroederCarrie L Langstraat Viktoriya Paroder Yulia LakhmanKrysten SoldanKaty Su Ginger J GardnerVaagn AndikyanJianxia GuoElizabeth L JewellKara Long RocheTiffany Troso-Sandoval Stuart M LichtmanLea A MoukarzelKimberly DessourcesNadeem R Abu-RustumCarol AghajanianWilliam P Tew Jan H Beumer Yukio Sonoda Roisin E O'Cearbhaill

Published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2021)

HIPEC with carboplatin was well tolerated but did not result in superior clinical outcomes. This study does not support the use of HIPEC with carboplatin during secondary cytoreductive surgery for platinum-sensitive recurrent ovarian cancer.

Keyphrases

phase ii study
locally advanced
open label
rectal cancer
minimally invasive
squamous cell carcinoma
radiation therapy
placebo controlled
coronary artery bypass
phase iii
coronary artery disease
atrial fibrillation