Mepolizumab reduces exacerbations in patients with severe eosinophilic asthma, irrespective of body weight/body mass index: meta-analysis of MENSA and MUSCA.

Frank C AlbersAlberto PapiCamille TailléDaniel J BrattonEric S BradfordSteven W YanceyNamhee Kwon

Published in: Respiratory research (2019)

This manuscript is a post hoc meta-analysis of data from the Phase 3 studies MENSA and MUSCA. ClinicalTrials.gov, NCT01691521 (MEA115588; MENSA). Registered September 24, 2012. ClinicalTrials.gov, NCT02281318 (200862; MUSCA). Registered November 3, 2014.

Keyphrases

body weight
chronic obstructive pulmonary disease
body mass index
cystic fibrosis
lung function
electronic health record
big data
weight gain
physical activity
early onset
case control
machine learning
data analysis