Amnestic and non-amnestic symptoms of dementia: An international study of Alzheimer's disease in people with Down's syndrome.

Luciana Mascarenhas FonsecaConcepcion PadillaElizabeth JonesNatalie NealeGlenda G HaddadGuilherme P MattarEriton BarrosIsabel C H ClareGeraldo F BusattoCassio M C BottinoMarcelo Q HoexterAnthony J HollandShahid Zaman

Published in: International journal of geriatric psychiatry (2020)

Premorbid amnestic and non-amnestic symptoms as reported by informants increase with the progression to AD. For the formal diagnosis of AD in DS this progression of symptoms needs to be taken into account. An understanding of the unique clinical presentation of DS in AD should inform treatment options.

Keyphrases

mild cognitive impairment
cognitive decline
sleep quality
case report
physical activity
depressive symptoms