Prenatal intake of omega-3 promotes Wnt/β-catenin signaling pathway, and preserves integrity of the blood-brain barrier in preeclamptic rats.

Asmaa Mohammed ShamsEldeenMarwa Nagi MehesenBasma Emad AboulhodaLaila Ahmed RashedMohamed Mahmoud ElsebaieEnas Ahmed MohamedMaha Mohammed Gamal

Published in: Physiological reports (2022)

Wnt/β-catenin signaling pathway suspected to have an important role to improve BBB integrity. Neuroprotective, antioxidant, and anti-inflammatory effects of omega-3 were observed and can be suggested as protective supplementation for preeclampsia.

Keyphrases

anti inflammatory
cell proliferation
stem cells
blood brain barrier
pregnant women
early onset
oxidative stress
pulmonary embolism
cerebral ischemia
pregnancy outcomes
physical activity
weight loss