Effect of semaglutide 2.4 mg on physical functioning and weight- and health-related quality of life in adults with overweight or obesity: Patient-reported outcomes from the STEP 1-4 trials.

Domenica M Rubino Jakob Bue BjornerNaveen RathorArya M SharmaLisa von Huth SmithSean Wharton Thomas A WaddenNiels ZeuthenRonette L Kolotkin

Published in: Diabetes, obesity & metabolism (2024)

Semaglutide 2.4 mg significantly improved physical functioning, with greater proportions of participants achieving MWPC compared with placebo, and showed beneficial effects on WRQOL and HRQOL beyond physical functioning.

Keyphrases

physical activity
patient reported
weight loss
mental health
weight gain
insulin resistance
metabolic syndrome
body mass index
adipose tissue
clinical trial
high fat diet induced