Modulation of cytokine patterns and microbiome during pregnancy in IBD.
Janine van der GiessenDana BinyaminAnna BelogolovskiSigal FrishmanKinneret Tenenbaum-GavishEran HadarYoram LouzounMaikel Petrus PeppelenboschChristien Janneke van der WoudeOmry KorenGwenny Manel FuhlerPublished in: Gut (2019)
Serum proinflammatory cytokine levels markedly improve on conception in pregnant patients with IBD, and intestinal microbiome diversity of patients with IBD normalises during middle and late pregnancy. We thus conclude that pregnancy is safe and even potentially beneficial for patients with IBD.