The association between ambient UVB dose and ANCA-associated vasculitis relapse and onset.
Jennifer ScottEnock HavyarimanaAlbert Navarro-GallinadArthur WhiteJason WyseJos van GeffenMichiel van WeeleAntonia BuettnerTamara WanigasekeraCathal WalshLouis AslettJohn D KelleherJulie PowerJames NgDeclan O'SullivanLucy HedermanNeil BasuMark A LittleLina Zgaganull nullPublished in: Arthritis research & therapy (2022)
Our findings suggest that low winter ambient UVB and prolonged vitD status contribute to AAV relapse risk across all phenotypes. However, the development of a granulomatous phenotype does not appear to be directly vitD-mediated. Further research is needed to determine whether sufficient vitD status would reduce relapse propensity in AAV.