Comparison of two porcine acute lung injury models: a post-hoc analysis.

René RisselMiriam RenzKatja MohnkeJulian RiedelKatharina RitterAlexander ZiebartRobert RuemmlerErik K HartmannJens Kamuf

Published in: Intensive care medicine experimental (2022)

Both animal ARDS models are feasible and are similar to human presentation of ARDS. If your respiratory research focus on hemodynamic/inflammation variables, the LPS-induced ARDS is a feasible model. Studying different ventilator strategies, the double-hit ARDS model offers a suitable approach.

Keyphrases

acute respiratory distress syndrome
lps induced
mechanical ventilation
extracorporeal membrane oxygenation
inflammatory response
endothelial cells
lipopolysaccharide induced
oxidative stress