Transcriptome-wide m6A profiling reveals mRNA post-transcriptional modification of boar sperm during cryopreservation.

Ziyue QinWencan WangMalik Ahsan AliYihan WangYan ZhangMing ZhangGuangbin ZhouJian-Dong YangChang-Jun Zeng

Published in: BMC genomics (2021)

Our study is the first to reveal the dynamic m6A modification of mRNAs in boar sperm during cryopreservation. These epigenetic modifications may affect mRNA expression and are closely related to sperm motility, apoptosis, and metabolism, which will provide novel insights into understanding of the cryoinjuries or freezability of boar sperm during cryopreservation.

Keyphrases

gene expression
single cell
genome wide
oxidative stress
transcription factor
cystic fibrosis
cell cycle arrest
staphylococcus aureus