Saddle nose deformity and septal perforation in granulomatosis with polyangiitis.
Annekatrin CoordesS M LooseV M HofmannG S HamiltonF RiedelD J MengerAndreas E AlbersPublished in: Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery (2017)
This study systematically reviews the efficacy and safety of surgical reconstruction of external nasal deformities in GPA patients for the first time. Saddle nose reconstruction in GPA patients with minimal or no local disease is a safe procedure despite an increased rate of revision surgery. Further research is required regarding the impact of antibiotic prophylaxis, immune-modulating therapy, long-term outcomes and functional outcomes measured with subjective and objective parameters.
Keyphrases
- end stage renal disease
- minimally invasive
- ejection fraction
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- total knee arthroplasty
- prognostic factors
- signaling pathway
- stem cells
- heart failure
- coronary artery disease
- total hip arthroplasty
- acute coronary syndrome
- depressive symptoms
- left ventricular
- physical activity
- cell therapy
- percutaneous coronary intervention