French national cohort of neuroendocrine cell hyperplasia of infancy (FRENCHI) study: diagnosis and initial management.
Candice FabreCaroline ThumerelleMorgane DervauxRola Abou-TaamTiphaine BihoueeJacques BrouardAnnick ClementChristophe DelacourtCéline DelestrainRalph EpaudSofiane GhdifanAlice HadchouelVéronique HoudouinGéraldine LabouretCaroline PerissonPhilippe ReixMarie-Catherine RenouxFrançoise TroussierLaurence WeissJulie MazenqNadia NathanJean-Christophe DubusPublished in: European journal of pediatrics (2022)
•In this national cohort of 54 patients with a NEHI pattern, diagnosis is mainly based on clinical symptoms and chest CT-scan results. The newly proposed clinical score and, when performed, the lung biopsies are faulted in 25 and 50% of the cases, respectively. •Corticosteroids are widely used. Such results plead for a new composite score to formally diagnose NEHI.