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Prevalence of Herpes Simplex and Varicella-Zoster Virus DNA in Corneal Grafts Is Higher than Expected.

Marie Ella HorstmannMohammad Al HaririStephanie D GrabitzJulia Bing BuMelissa ApelNorbert PfeifferJoanna Wasielica-Poslednik
Published in: Microorganisms (2023)
The prevalence of herpes DNA in the donor corneas was 8.2% and thus higher than previously reported. We did not notice any evidence for a donor-to-host transmission, but a higher rate of postoperative complications in recipients of the grafts with viral DNA. The donors with and without herpetic DNA did not differ significantly regarding systemic diagnoses or cultural conditions, but sepsis was more frequent in the group with viral DNA.
Keyphrases
  • circulating tumor
  • cell free
  • single molecule
  • risk factors
  • nucleic acid
  • intensive care unit
  • optical coherence tomography