The role of TPA I/D and PAI-1 4G/5G polymorphisms in multiple sclerosis.

Maja ZivkovićNada Starčević ČizmarevićLuca LovrečićInge Klupka-SarićAleksandra StankovićIva GašparovićPolona LavtarEvica DinčićLjiljana StojkovićGorazd RudolfSaša Sega JazbecOlivio PerkovićOsman SinanovićJuraj SepčićMiljenko KapovićBorut PeterlinSmiljana Ristić

Published in: Disease markers (2014)

We found a significantly harmful effect of the combination of the PAI-1 5G/5G genotype and TPA I allele on MS susceptibility, which indicates the importance of gene-gene interactions in complex diseases such as MS.

Keyphrases

multiple sclerosis
mass spectrometry
copy number
genome wide
ms ms
white matter
dna methylation
genome wide analysis