Infection risk in sarcoidosis patients treated with methotrexate compared to azathioprine: A retrospective 'target trial' emulated with Swedish real-world data.

Marios RossidesSusanna KullbergDaniela Di GiuseppeAnders EklundJohan GrunewaldJohan AsklingElizabeth V Arkema

Published in: Respirology (Carlton, Vic.) (2021)

Methotrexate appears to be associated with a lower risk of infection in sarcoidosis than azathioprine, but randomized trials should confirm this finding.

Keyphrases

high dose
clinical trial
study protocol
electronic health record
phase iii
big data
phase ii