Systemic mastocytosis: 2023 update on diagnosis and management in adults.

Alessandro CostaEmilia ScalzulliIda CarmosinoMarcello CapriataClaudia IeloChiara MasucciMauro PassucciMaurizio Martelli Massimo Breccia

Published in: Expert opinion on emerging drugs (2023)

Diagnosis and classification of SM has evolved over years. The most recent WHO and ICC classification improved SM diagnostic work-up, providing clinicians with a clear and simplified diagnostic scheme. New approved targeted therapies such as midostaurin and avapritinib modified the treatment paradigm in patients in advanced stage, and next-generation inhibitors actually investigated in clinical trials are expected in the next future.

Keyphrases

clinical trial
end stage renal disease
machine learning
deep learning
newly diagnosed
chronic kidney disease
ejection fraction
prognostic factors
palliative care
peritoneal dialysis
patient reported
atomic force microscopy
open label
high resolution
study protocol
drug induced
mass spectrometry