Veno-venous ECMO as a platform to evaluate lung lavage and surfactant replacement therapy in an animal model of severe ARDS.

Robert QaqishYui WatanabeMarcos GalassoCara SummersA Adil AliMamoru TakahashiAnajara GazzalleMingyao LiuShaf KeshavjeeMarcelo CypelLorenzo Del Sorbo

Published in: Intensive care medicine experimental (2020)

A clinically relevant severe ARDS pig model requiring ECMO was established. Bronchoscopic saline lavage and SRT during ECMO did not provide a significant physiologic benefit compared to controls.

Keyphrases

extracorporeal membrane oxygenation
acute respiratory distress syndrome
replacement therapy
respiratory failure
mechanical ventilation
early onset
smoking cessation
high throughput
drug induced
intensive care unit