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Variant profiles of genes mapping to chromosome 16q loss in Wilms tumors reveals link to cilia-related genes and pathways.

Eiko KitamuraJohn K CowellChang-Sheng ChangLesleyann Hawthorn
Published in: Genes & cancer (2020)
The data suggest that cilia-related genes and pathways are compromised in Wilms tumors. The genes on chromosome 16q that carry deleterious variants in cilia-related genes may account for the more aggressive nature of tumors with 16q del/LOH.
Keyphrases
  • copy number
  • genome wide
  • high resolution
  • bioinformatics analysis
  • electronic health record
  • dna methylation
  • big data
  • gene expression
  • mass spectrometry
  • data analysis