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Influence of Mechanical Ventilation Modes on the Efficacy of Nebulized Bronchodilators in the Treatment of Intubated Adult Patients with Obstructive Pulmonary Disease.

Cibelle Andrade LimaShirley Lima CamposMonique Pontes BandeiraWagner Souza LeiteDaniella Cunha BrandãoJuliana FernandesJames B FinkArmele de Fátima Dornelas de Andrade
Published in: Pharmaceutics (2023)
Nebulized bronchodilators reduce the aeration of non-dependent pulmonary regions and increase overall lung ventilation but there was no difference between the ventilation modes. As a limitation, it is important to note that the muscular effort in PSV and A/C PCV modes influences the impedance variation, and consequently the aeration and ventilation values. Thus, future studies are needed to evaluate this effort as well as the time on ventilator, time in UCI and other variables.
Keyphrases
  • mechanical ventilation
  • respiratory failure
  • acute respiratory distress syndrome
  • intensive care unit
  • pulmonary hypertension
  • extracorporeal membrane oxygenation
  • current status