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Role of heme oxygenase-1 in the antidepressant-like effect of ursolic acid in the tail suspension test.

Ana Belen Ramos-HrybFrancis L PaziniAna Paula CostaMauricio P CunhaManuella P KasterAna Lúcia S Rodrigues
Published in: The Journal of pharmacy and pharmacology (2021)
In conclusion, this work shows that increased hippocampal HO-1 content and activity mediate the antidepressant-like effect of UA in the TST.
Keyphrases
  • major depressive disorder
  • bipolar disorder
  • pi k akt
  • cerebral ischemia
  • blood brain barrier