Relationship between self-rated pain and peri-implant clinical, radiographic and whole salivary inflammatory markers among patients with and without peri-implantitis.

Proinflammatory cytokines (IL-1β, IL-6, and TNF-α) are more often expressed in the UWS of patients with than without peri-implantitis. However, the correlation between self-rated pain and whole salivary proinflammatory cytokine profile in patients with peri-implantitis remains unclear.