Evaluation of kidney function in HIV-infected patients receiving an antiretroviral regimen containing one or two inhibitors of the tubular secretion of creatinine.
José Luis CasadoM MonsalvoPilar VizcarraM FontechaS Serrano-VillarSantiago MorenoPublished in: HIV medicine (2019)
Similar eGFR-scr decreases were observed in patients using different antiretroviral drugs inhibiting the tubular transport of creatinine, separately or in combination, with no alterations in proteinuria or cystatin C-based eGFR. The lack of additional changes when the drugs were used in combination, and the lower impact in cases of previous chronic kidney disease, suggest that there are compensatory mechanisms for creatinine secretion.
Keyphrases
- hiv infected
- end stage renal disease
- chronic kidney disease
- small cell lung cancer
- antiretroviral therapy
- human immunodeficiency virus
- uric acid
- epidermal growth factor receptor
- peritoneal dialysis
- tyrosine kinase
- hiv aids
- newly diagnosed
- ejection fraction
- hiv positive
- hiv infected patients
- prognostic factors
- signaling pathway
- metabolic syndrome
- hepatitis c virus
- endothelial cells
- drug induced
- patient reported outcomes
- men who have sex with men
- patient reported
- south africa