Incremental diagnostic value of [18F]tetrafluoroborate PET-CT compared to [131I]iodine scintigraphy in recurrent differentiated thyroid cancer.

Matthias DittmannJosé Manuel Gonzalez CarvalhoKambiz RahbarMichael SchäfersMichael ClaesenerBurkhard RiemannRobert Seifert

Published in: European journal of nuclear medicine and molecular imaging (2020)

In the present cohort, [18F]TFB-PET shows higher sensitivity and accuracy than [131I]iodine WBS and SPECT-CT in detecting recurrent DTC. The combination of [18F]TFB-PET with [18F]FDG-PET-CT seems a reasonable strategy to characterize DTC tumor manifestations with respect to their differentiation and thereby also individually plan and monitor treatment. Future prospective studies evaluating the potential of [18F]TFB-PET in recurrent DTC are warranted.

Keyphrases

pet ct
positron emission tomography
dual energy
computed tomography
magnetic resonance
contrast enhanced
pet imaging
risk assessment