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Genomic targets for high-resolution inference of kinship, ancestry and disease susceptibility in orang-utans (genus: Pongo).

Graham L BanesEmily D FountainAlyssa KarklusHao-Ming HuangNian-Hong Jang-LiawDaniel L BurgessJennifer WendtCynthia MoehlenkampGeorge F Mayhew
Published in: BMC genomics (2020)
Our targets are of broad utility in studies of orang-utan ancestry, admixture and disease susceptibility and aetiology, and thus are of value in addressing questions key to the survival of these species. To facilitate comparative analyses, these targets could now be standardized for future orang-utan population genomic studies. The targets are broadly compatible with commercial target enrichment platforms and can be utilized as published here to synthesize applicable probes.
Keyphrases
  • high resolution
  • copy number
  • small molecule
  • gene expression
  • systematic review
  • single cell
  • current status
  • single molecule
  • living cells