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Comparison of Recombinant MVA Selection Methods Based on F13L, D4R and K1L Genes.

Irina V AntoshkinaDina V GlazkovaFelix Anatolevich UrusovElena Vladimirovna BogoslovskayaGerman A Shipulin
Published in: Viruses (2022)
Modified vaccinia Ankara (MVA) is a promising vaccine vector due to its highly attenuated phenotype and good immunogenicity. However, obtaining a new recombinant MVA remains a tedious and laborious procedure involving many rounds of plaque purification. Recombinant MVA generation can be greatly improved and facilitated by different selection techniques. Here, we describe a comparison between techniques based on K1L, F13L and D4R genes.
Keyphrases
  • genome wide
  • cell free
  • bioinformatics analysis
  • coronary artery disease
  • gene expression
  • genome wide analysis