The dark side of apnea: altered 24-hour melatonin secretion in obstructive sleep apnea (OSAS) is disease severity dependent.

Peter KarelMirella SchilperoordLoes J A Reichman Johannes G Krabbe

Published in: Sleep & breathing = Schlaf & Atmung (2024)

This study describes clear OSAS severity dependent abnormalities in melatonin production in OSAS patients, independent of sex and/or age. Future research should indicate whether oral melatonin supplementation has beneficial effects in OSAS patients with attenuated endogenous melatonin production.

Keyphrases

obstructive sleep apnea
end stage renal disease
positive airway pressure
ejection fraction
chronic kidney disease
newly diagnosed
blood pressure
peritoneal dialysis
prognostic factors
patient reported outcomes