Alteration of calcium signalling in cardiomyocyte induced by simulated microgravity and hypergravity.

Caizhi LiuGuohui ZhongYuezhang ZhouYuchen YangYingjun TanYuheng LiXingcheng GaoWeijia SunJianwei LiXiaoyan JinDengchao CaoXinxin YuanZizhong LiuShuai LiangYouyou LiRuikai DuYinlong ZhaoJianqi XueDingsheng ZhaoJinping SongShukuan LingYingxian Li

Published in: Cell proliferation (2020)

Our study demonstrates for the first time that Ca2+ /CaMKII/HDAC4 signalling plays a pivotal role in myocardial remodelling under rotation-simulated microgravity and hypergravity.

Keyphrases

left ventricular
histone deacetylase
atrial fibrillation
high glucose