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The Effects Study of Isoniazid Conjugated Multi-Wall Carbon Nanotubes Nanofluid on Mycobacterium tuberculosis.

Shahab ZomorodbakhshYasamin AbbasianMaryam NaghinejadMojgan Sheikhpour
Published in: International journal of nanomedicine (2020)
Since one of the main antimicrobial mechanisms of MWCNTs is through the destruction of the bacterial cell wall, in addition to its antimicrobial effects, it increased the drug delivery of INH at lower doses compared to drug alone. So, the nanofluid, containing INH-conjugated MWCNTs, had a better lethal effect on a variety of M.tb strains than that of the drug alone.
Keyphrases
  • mycobacterium tuberculosis
  • carbon nanotubes
  • drug delivery
  • cell wall
  • staphylococcus aureus
  • escherichia coli
  • pulmonary tuberculosis
  • emergency department
  • adverse drug